Heroes Wear Masks is a modifed Pathfinder rpg for the superhero genre. Here is a blurb from the game,

"Heroes Wear Masks is Pathfinder after it was bitten by a radioactive spider. If you're familiar with Pathfinder you'll recognize most of the rules. If you're familiar with superheroes you'll be familiar with most of the setting. If you're familiar with both, you'll be right at home here."